Prognosis and Treatment of Desquamative Inflammatory Vaginitis

@article{Sobel2011PrognosisAT,
  title={Prognosis and Treatment of Desquamative Inflammatory Vaginitis},
  author={J Sobel and Orna Reichman and D. Misra and Wonsuk Yoo},
  journal={Obstetrics \& Gynecology},
  year={2011},
  volume={117},
  pages={850-855}
}
OBJECTIVE: Desquamative inflammatory vaginitis is a clinical syndrome frequently unrecognized, characterized by vaginal rash and purulent discharge. We describe patient outcomes and treatment at follow-up in a case series of 98 women diagnosed with this syndrome. METHODS: We performed a chart review of 130 patients diagnosed with desquamative inflammatory vaginitis between 1996 and 2007 in a referral university-based vaginitis clinic. Clinical findings, laboratory findings, and treatment were… Expand
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References

SHOWING 1-10 OF 15 REFERENCES
Desquamative inflammatory vaginitis: a new subgroup of purulent vaginitis responsive to topical 2% clindamycin therapy.
  • J. Sobel
  • Medicine
  • American journal of obstetrics and gynecology
  • 1994
TLDR
Evidence suggests a microbial, possibly gram-positive coccal, cause for this syndrome, although a specific bacterial species responsible for all cases has not been identified, represents an uncommon cause of purulent vaginitis with unique clinical and laboratory characteristics. Expand
Desquamative inflammatory vaginitis. A review.
TLDR
Its causation and natural history remain largely unknown and there is as yet, insufficient evidence to regard it as a single entity, but it is likely that the incidence of the disorder is underestimated. Expand
VAGINITIS IN WOMEN, DIAGNOSIS AND TREATMENT.
TLDR
The Trichomonas vaginalis disappeared from the vaginas of 158 women after treatment with metronidazole, and vaginal discharge and irritation due to Candida albicans and Hemophilus vaginalis represent primarily an infection of the secretions, rather than inflammation of the vaginal wall. Expand
Desquamative Vaginitis: Lichen Planus in Disguise
TLDR
Early recognition of the disorder and prompt use of corticosteroids and vaginal dilators may prevent the common sequelae of adhesion formation and vaginal stenosis. Expand
Clinical implications of the immunomodulatory effects of macrolides on sinusitis.
  • Y. Majima
  • Medicine
  • The American journal of medicine
  • 2004
TLDR
In vivo and in vitro studies show that some macrolides affect neutrophil chemotaxis and infiltration, inflammatory cytokine production, mucus production, and the transportability of airway secretions, indicating that macrolide are promising agents for treating chronic inflammation of the airways. Expand
Desquamative inflammatory vaginitis: a newly defined entity.
  • H. L. Gardner
  • Medicine
  • American journal of obstetrics and gynecology
  • 1968
TLDR
Eight cases of a newly described type of vaginitis, which appears in women with normal estrogen levels, which resembles atrophic vag in many respects, although it appears inWomen with normal testosterone levels are reported. Expand
An Overview of Topical Antibiotics for Acne Treatment
TLDR
A review of the articles published in the past 30 years revealed that topical application of antibiotics showed clinical effectiveness for mild to moderate inflammatory acne, especially when they are combined with zinc, tretinoin or benzoyl peroxide, while they showed little influence on noninflammatory acne. Expand
Anti-inflammatory effects of macrolides--an underappreciated benefit in the treatment of community-acquired respiratory tract infections and chronic inflammatory pulmonary conditions?
  • G. Amsden
  • Medicine
  • The Journal of antimicrobial chemotherapy
  • 2005
TLDR
Research into macrolide immunomodulation for chronic pulmonary disorders demonstrates consistent positive effects, although of types other than seen with diffuse panbronchiolitis, which has the potential to make them a useful option. Expand
The effect of antimicrobial agents on leukocyte chemotaxis.
TLDR
It is postulated that the capacity of some of these agents to inhibit leukocyte chemotaxis may account, in part, for their efficacy in inflammatory skin diseases such as acne vulgaris. Expand
Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria
TLDR
The details of antibiotic interactions with the components of their binding sites are reported and the importance of putative Mg+2 ions for the binding of some drugs is shown to facilitate rational drug design. Expand
...
1
2
...