Prognosis Value of Platelet Counts, Albumin and Neutrophil-Lymphocyte Ratio of Locoregional Recurrence in Patients with Operable Head and Neck Squamous Cell Carcinoma

@article{Ye2020PrognosisVO,
  title={Prognosis Value of Platelet Counts, Albumin and Neutrophil-Lymphocyte Ratio of Locoregional Recurrence in Patients with Operable Head and Neck Squamous Cell Carcinoma},
  author={Jing Ye and Bing Liao and Xiaohua Jiang and Zhihuai Dong and Sunhong Hu and Yuehui Liu and Mang Xiao},
  journal={Cancer Management and Research},
  year={2020},
  volume={12},
  pages={731 - 741}
}
Background Peripheral blood inflammation factor neutrophil-lymphocyte ratio (NLR), platelet count (PLT) and nutritional factor serum albumin (ALB) have been proposed as prognostic markers of head and neck squamous carcinoma cancer (HNSCC) in recent years. In the current study, nomogram predict models based on pre-treatment hematological parameters and a modified risk-stratified score system have been built. Methods A total of 197 patients with oropharyngeal, hypopharyngeal and laryngeal cancers… 

Figures and Tables from this paper

The predictive value of a preoperative systemic immune‐inflammation index and prognostic nutritional index in patients with esophageal squamous cell carcinoma

TLDR
The results demonstrate that the preoperative high SII and low PNI are powerful indicators of aggressive biology and poor prognosis for patients with ESCC and the combination of S II and PNI can enhance the accuracy of prognosis.

Pre‐treatment neutrophil‐to‐lymphocyte ratio is an independent prognostic factor in head and neck squamous cell carcinoma: Meta‐analysis and trial sequential analysis

  • Pierluigi MarianiD. Russo L. Laino
  • Medicine
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • 2021
TLDR
A higher value of pre‐treatment NLR correlates with a statistically significant decrease of OS and a lower DFS in patients with primary head and neck squamous cell carcinoma treated by surgery alone or followed by chemo/radiotherapy in HNSCC patients.

Prognostic implications of preoperative systemic inflammatory markers in oral squamous cell carcinoma, and correlations with the local immune tumor microenvironment

TLDR
Preoperative NLR, SII, and LMR may serve as valuable systemic markers to predict OSCC patient survival, with NLR emerging as an independent predictor of poor OS.

Pretreatment Blood Markers in the Prediction of Occult Neck Metastasis: A 10-Year Retrospective Study

TLDR
This study supports the role of pretreatment NLR in predicting occult neck metastasis in early-stage OSCC of the tongue and sheds some light over the potential of NLR as a predictor of the primary tumor’s DOI.

Geriatric nutritional risk index as a prognostic marker of pTNM-stage I and II esophageal squamous cell carcinoma after curative resection

TLDR
The geriatric nutritional risk index (GNRI) is associated with mortality in several malignancies and preoperative GNRI may sort patients into low- or high-risk groups for shorter CSS, especially in those with pTNM stage I and II ESCC.

Development and validation of a nomogram to predict cancer-specific survival in patients with hypopharyngeal squamous cell carcinoma treated with primary surgery

TLDR
A nomogram was established that was superior to conventional AJCC staging in predicting cancer-specific survival (CSS) in patients with hypopharyngeal squamous cell carcinoma treated with primary surgery to provide more accurate risk stratification for patients.

Systemic Immune-Inflammation Index Is a Prognostic Factor for Breast Cancer Patients After Curative Resection

TLDR
Preoperative SII is a simple and useful prognostic factor for predicting long-term outcomes for breast cancer patients undergoing surgery and was significantly associated with prognosis in all subtypes.

Comparison of Selected Immune and Hematological Parameters and Their Impact on Survival in Patients with HPV-Related and HPV-Unrelated Oropharyngeal Cancer

TLDR
This study confirmed that determination of HPV etiology as well as analysis of various hematological and immune parameters should be a standard management in OPC patients in order to properly treat them for improved prognosis.

Prognosis in Head and Neck Cancer: Importance of Nutritional and Biological Inflammatory Status

  • N. SaroulM. Puechmaille L. Gilain
  • Medicine
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • 2021
TLDR
Prognosis in head and neck cancer is multifactorial; however, malnutrition and inflammation are important factors that are potentially reversible by early intervention.

A predictive model for early recurrence of colorectal-cancer liver metastases based on clinical parameters

TLDR
A bedside model based on clinical parameters to predict early recurrence in CRLM patients after curative surgery showed superior performance and could aid in the decision-making for selective follow-up strategies.

References

SHOWING 1-10 OF 40 REFERENCES

Relation of baseline neutrophil-to-lymphocyte ratio to survival and toxicity in head and neck cancer patients treated with (chemo-) radiation

TLDR
In HNSCC patients treated with primary or adjuvant (C)RT, NLR is an independent predictor of mortality, but not disease-specific outcomes or toxicity, and may be used for risk-stratification.

Preoperative circulating platelet, neutrophil, and lymphocyte counts predict survival in oral cancer.

TLDR
Findings indicate that preoperative circulating platelets, neutrophils, lymphocytes, and PNL score serve as noninvasive, low-cost, and powerful prognostic predictors for patients with OSCC.

The predictive value of a preoperative systemic immune‐inflammation index and prognostic nutritional index in patients with esophageal squamous cell carcinoma

TLDR
The results demonstrate that the preoperative high SII and low PNI are powerful indicators of aggressive biology and poor prognosis for patients with ESCC and the combination of S II and PNI can enhance the accuracy of prognosis.

Prognostic impact of the combination of neutrophil-to-lymphocyte ratio and Glasgow prognostic score in colorectal cancer: a retrospective cohort study

TLDR
Combination of NLR and GPS can be a novel scoring system to effectively stratify outcome in CRC and demonstrate prognostic importance in colorectal cancer.

Correlation of Inflammatory Markers, Survival, and COX2 Expression in Oral Cancer and Implications for Prognosis

  • Y. SanoYasunao Kogashiwa M. Sugasawa
  • Medicine
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • 2018
TLDR
Pretreatment inflammatory markers are useful as prognostic factors in advanced OSCC and the study suggests that local COX2 may be affected by systemic inflammation and that the prognostic impact ofCOX2 expression depends on host factors and tumor characteristics.

The prognostic significance of the neutrophil-to-lymphocyte ratio and the platelet-to-lymphocyte ratio in giant cell tumor of the extremities

TLDR
As a novel inflammatory index, NLR has some predictive power for the prognosis of patients with giant cell tumor of the extremities.

The prognostic value of pre-treatment prognostic nutritional index in esophageal squamous cell carcinoma

TLDR
Low pre-treatment PNI was significantly related with OS and recurrence free survival but not CSS for ESCC, and higher stage ESCC have higher incidence of low PNI.

Prognostic value of pretherapy platelet elevation in oropharyngeal cancer patients treated with chemoradiation

TLDR
Pretreatment platelet elevation is a promising predictor of prognosis, and further work should be done to elucidate the utility of antiplatelets in modifying risk in OPC patients.

Association Between Lymph Node Ratio and Recurrence and Survival Outcomes in Patients With Oral Cavity Cancer

TLDR
The findings from this study suggest that LNR is the most robust prognostic factor appears to have disease, and nonwhite patients with primary OCSCC are found to be associated with worse outcomes.

Cervical Lymph Node Metastatic Status and Adjuvant Therapy Predict the Prognosis of Salivary Duct Carcinoma.