Proglumide prevents and curtails acute tolerance to morphine in rats
@article{Tang1984ProglumidePA, title={Proglumide prevents and curtails acute tolerance to morphine in rats}, author={J. Tang and J. Chou and Michael J. Iadarola and H. -Y. T. Yang and Erminio Costa}, journal={Neuropharmacology}, year={1984}, volume={23}, pages={715-718} }
81 Citations
Enhancement of morphine analgesia and prevention of morphine tolerance in the rat by the cholecystokinin antagonist L-364,718.
- BiologyEuropean journal of pharmacology
- 1988
Cholecystokinin receptor binding in morphine analgesia: Tolerance, withdrawal and abstinence
- BiologyNeuropeptides
- 1994
Caerulein changes morphine-induced antinociception depending on pretreatment times.
- BiologyGeneral pharmacology
- 1994
Dissociation of tolerance and dependence to morphine: a possible role for cholecystokinin
- Biology, PsychologyBrain Research
- 1987
Chronic administration of cholecystokinin antagonists reverses the enhancement of spinal morphine analgesia induced by acute pretreatment
- Biology, PsychologyBrain Research
- 1990
CI988, a selective antagonist of cholecystokininB receptors, prevents morphine tolerance in the rat
- Biology, MedicineBritish journal of pharmacology
- 1992
Evidence is provided that chronic treatment with a selective CCKB receptor antagonist could prevent tolerance to the analgesic effect of morphine without affecting morphine‐induced physical dependence and by eliminating the need to increase morphine doses to unacceptable levels.
Caerulein-induced antinociception: Interaction with morphine and opioid antagonists in the rat
- Biology, MedicineNeuropeptides
- 1989
Naloxone, not proglumide or MK-801, alters effects of morphine preexposure on morphine-induced taste aversions
- Biology, PsychologyPharmacology Biochemistry and Behavior
- 2006
References
SHOWING 1-9 OF 9 REFERENCES
Antagonism of morphine-induced catalepsy by L-prolyl-L-leucyl-glycinamide.
- BiologyEuropean journal of pharmacology
- 1979
Peptide inhibitor of morphine- and beta-endorphin-induced analgesia.
- Biology, ChemistryProceedings of the National Academy of Sciences of the United States of America
- 1980
The synthetic beta-endorphin analogs with the omission of the NH2-terminal [Met]enkephalin segment are shown to inhibit morphine- or beta-Endorphin-induced analgesia in mice by the tail-flick test, raising the possibility that endogenous inhibiting peptides exist in the brain which play a role in the regulation of endorphin actions.
Opiate and peptide interaction: effect of enkephalins on morphine analgesia.
- Biology, ChemistryEuropean journal of pharmacology
- 1980
Proglumide: selective antagonism of excitatory effects of cholecystokinin in central nervous system.
- Biology, MedicineScience
- 1983
Intravenous and iontophoretic proglumide administration consistently blocked cholecystokinin-induced excitations while having no effect on glutamic acid-induced increases in activity, suggesting that this drug may be valuable for studying the possible role of chole Cytokine as a neurotransmitter or neuromodulator in the central nervous system.
Studies on the location and release of cholecystokinin and vasoactive intestinal peptide in rat and cat spinal cord
- BiologyBrain Research
- 1982
Evidence for the neuropeptide cholecystokinin as an antagonist of opiate analgesia.
- Biology, PsychologyScience
- 1983
A physiological role for cholecystokinin as a specific opiate antagonist in analgesia-mediating systems is suggested and a similar mode of action may explain other behavioral effects of chole CyStokinin, such as suppression of food intake.
Effects of Pro‐Leu‐Gly‐NH2 (MIF) on the antinociceptive and thermoregulatory actions of morphine and oxotremorine
- Biology, MedicineThe Journal of pharmacy and pharmacology
- 1982
Recently, it was demonstrated that MIF antagonizes morphine's antinociceptive action when given chronically to rats (Dickinson & Slater 1980), and more data is presented on chronic MIF and morphine's thermoregulatory and antinOCiceptive actions.
Possible interaction between cholecystokinin and dopamine.
- PsychologyAdvances in biochemical psychopharmacology
- 1982