Progestogens and membrane-initiated effects on the proliferation of human breast cancer cells

@article{Ruan2012ProgestogensAM,
  title={Progestogens and membrane-initiated effects on the proliferation of human breast cancer cells},
  author={X. Ruan and H. Neubauer and Y. Yang and H. Schneck and S. Schultz and T. Fehm and M. Cahill and H. Seeger and A. Mueck},
  journal={Climacteric},
  year={2012},
  volume={15},
  pages={467 - 472}
}
  • X. Ruan, H. Neubauer, +6 authors A. Mueck
  • Published 2012
  • Medicine
  • Climacteric
  • ABSTRACT Objectives Evidence is accumulating that progestogens may play a crucial role in the development of breast cancer under contraception and hormone therapy in reproductive and menopausal women. Progesterone receptor membrane component 1 (PGRMC1) expressed in breast cancer may be important in tumorigenesis and thus may increase breast cancer risk. The aim of this project was to investigate the influence of progesterone and nine synthetic progestins on MCF-7 breast cancer cells… CONTINUE READING
    40 Citations
    Membrane-receptor initiated proliferative effects of dienogest in human breast cancer cells
    • H. Schneck, X. Ruan, +4 authors H. Neubauer
    • Biology, Medicine
    • Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
    • 2013
    • 11
    Possible role of PGRMC1 in breast cancer development
    • 36
    Membrane-initiated effects of Serelys® on proliferation and apoptosis of human breast cancer cells
    • 9
    PGRMC1 can trigger estrogen-dependent proliferation of breast cancer cells: estradiol vs. equilin vs. ethinylestradiol
    • 4
    Progesterone receptor membrane component 1 promotes survival of human breast cancer cells and the growth of xenograft tumors
    • 27
    • PDF
    Nomegestrol acetate sequentially or continuously combined to estradiol did not negatively affect membrane-receptor associated progestogenic effects in human breast cancer cells
    • X. Ruan, H. Schneck, +7 authors H. Neubauer
    • Medicine
    • Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
    • 2012
    • 24
    • PDF

    References

    SHOWING 1-10 OF 49 REFERENCES
    New insight on a possible mechanism of progestogens in terms of breast cancer risk
    • 15
    • PDF
    The effect of progesterone and synthetic progestins on serum- and estradiol-stimulated proliferation of human breast cancer cells.
    • 49
    Membrane-initiated effects of progesterone on proliferation and activation of VEGF in breast cancer cells
    • H. Neubauer, G. Adam, +5 authors T. Fehm
    • Biology, Medicine
    • Climacteric : the journal of the International Menopause Society
    • 2009
    • 54
    • PDF