Progestogen therapies: differences in clinical effects?

@article{Wiegratz2004ProgestogenTD,
  title={Progestogen therapies: differences in clinical effects?},
  author={I. Wiegratz and H. Kuhl},
  journal={Trends in Endocrinology & Metabolism},
  year={2004},
  volume={15},
  pages={277-285}
}
A large number of estrogen/progestogen preparations are available for the treatment of estrogen-deficiency symptoms. These preparations differ in the route of administration, the type and dose of both the estrogen and progestogen. The only indication for the addition of a progestogen is endometrial protection, but, depending on its chemical structure, a progestogen can either enhance (e.g. hot flushes, gonadotropin release, breast-epithelial proliferation and bone mineral density) or antagonize… Expand
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