Progesterone treatment inhibits the inflammatory agents that accompany traumatic brain injury.

@article{Pettus2005ProgesteroneTI,
  title={Progesterone treatment inhibits the inflammatory agents that accompany traumatic brain injury.},
  author={Edward H. Pettus and David D. Wright and Donald G. Stein and Stuart W. Hoffman},
  journal={Brain research},
  year={2005},
  volume={1049 1},
  pages={112-9}
}
Progesterone given after traumatic brain injury (TBI) has been shown to reduce the initial cytotoxic surge of inflammatory factors. We used Western blot techniques to analyze how progesterone might affect three inflammation-related factors common to TBI: complement factor C3 (C3), glial fibrillary acidic protein (GFAP), and nuclear factor kappa beta (NFkappaB). One hour after bilateral injury to the medial frontal cortex, adult male rats were given injections of progesterone (16 mg/kg) for 2… CONTINUE READING
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