Progesterone receptors induce cell cycle progression via activation of mitogen-activated protein kinases.

Abstract

Progestins induce proliferation of breast cancer cells and are implicated in the development of breast cancer. The effects of progestins are mediated by progesterone receptors (PRs), although it is unclear whether proliferative effects are delivered through activities as ligand-activated transcription factors or via activation of cytoplasmic kinases. We… (More)

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@article{Skildum2005ProgesteroneRI, title={Progesterone receptors induce cell cycle progression via activation of mitogen-activated protein kinases.}, author={Andrew J. Skildum and Emily J. Faivre and C. De Lange}, journal={Molecular endocrinology}, year={2005}, volume={19 2}, pages={327-39} }