Progesterone receptor membrane component 1: An integrative review

@article{Cahill2007ProgesteroneRM,
  title={Progesterone receptor membrane component 1: An integrative review},
  author={Michael A Cahill},
  journal={The Journal of Steroid Biochemistry and Molecular Biology},
  year={2007},
  volume={105},
  pages={16-36}
}
Progesterone receptor membrane component 1 (PGRMC1) contains a cytochrome b5 domain fold and belongs to the so-called membrane-associated progesterone receptor (MAPR) protein family that is widespread in eukaryotes. PGRMC1 and the related PGRMC2 mammalian family member diverged sometime after the evolution of segmented metazoan body plan and the appearance of vertebrates. Therefore PGRMC1 might be expected to be involved in some ancient eukaryotic processes, as well as more modern functions… CONTINUE READING
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