Progesterone receptor distribution in the human endometrium. Analysis using monoclonal antibodies to the human progesterone receptor.

@article{Press1988ProgesteroneRD,
  title={Progesterone receptor distribution in the human endometrium. Analysis using monoclonal antibodies to the human progesterone receptor.},
  author={Michael F Press and J A Udove and Geoffrey L Greene},
  journal={The American journal of pathology},
  year={1988},
  volume={131 1},
  pages={
          112-24
        }
}
Two monoclonal antibodies to the human progesterone receptor (PR), JZB39 and KD68, were used in determining the immunohistochemical distribution of PR in the human endometrium throughout the menstrual cycle and after menopause. These antibodies recognized PR, as demonstrated by a downfield shift in the radiolabeled progestin binding peak when KD68 or JZB39 was added to high salt sucrose density gradients. The specificity of both antibodies for PR was confirmed with Western immunoblots and… CONTINUE READING
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