Progesterone metabolism in the pineal, brain stem, thalamus and corpus callosum of the female rat

@article{Hanukoglu1977ProgesteroneMI,
  title={Progesterone metabolism in the pineal, brain stem, thalamus and corpus callosum of the female rat},
  author={Israel Hanukoglu and Harry J. Karavolas and Robert w. Goy},
  journal={Brain Research},
  year={1977},
  volume={125},
  pages={313-324}
}
Progesterone metabolism by the hypothalamus, pituitary, and uterus of the rat during pregnancy.
TLDR
It is concluded that there are different profiles in the in vitro metabolism of [3H]progesterone by the hypothalamus, pituitary, and uterus of the rat during the course of pregnancy.
The effect of progesterone and its metabolites on the interictal epileptiform discharge in the cat's cerebral cortex.
TLDR
It is concluded that the pregnanolones have strong antiepileptic properties and the rapid onset of effect indicates that the steroids may interact with the neuronal function at the membrane or synaptic levels.
Preliminary Note Metabolism of Progesterone in Mouse Brain
TLDR
Comparison of the chromatographic behaviour of the unknown metabolite with that of authentic progesterone derivatives suggested that this metabolite corresponds to 20-hydroxy-4-pre gnene-3-one, and subcellular fractionation of mouse brain demonstrated a particulate location for the 5~-reduction of progester one and a cytosolic location forThe unknown major metabolite.
Metabolism of progesterone in mouse brain
Androgens and the Brain: Role of Testosterone Metabolism
TLDR
The brain must be viewed not only as an important target for steroid effects, but also as a structure which possesses the machinery for synthesizing hormone precursors and for metabolizing both these precursor and hormones originating in the peripheral steroidogenetic glands, in order to fulfill specific functional requirements.
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