Progesterone metabolism in the pineal, brain stem, thalamus and corpus callosum of the female rat

@article{Hanukoglu1977ProgesteroneMI,
  title={Progesterone metabolism in the pineal, brain stem, thalamus and corpus callosum of the female rat},
  author={Israel Hanukoglu and H. J. Karavolas and R. Goy},
  journal={Brain Research},
  year={1977},
  volume={125},
  pages={313-324}
}
  • Israel Hanukoglu, H. J. Karavolas, R. Goy
  • Published 1977
  • Biology, Medicine
  • Brain Research
  • Specific brain regions, namely, thalamus, tectum, tegmentum, cerebellum, medulla and pineal, from five proestrous rats were incubated for 30 min with [3H]progesterone. After reverse isotopic dilution analysis, the following metabolites were identified in all incubations by purification to constant specific activity, derivative formation and/or gas liquid chromatography trapping: [3H]5alpha-pregnane-3, 20-dione (10-20% of the starting substrate except pineal -- 0.7%), [3H]3alpha-hydroxy-5alpha… CONTINUE READING
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