Progesterone metabolism in the pineal, brain stem, thalamus and corpus callosum of the female rat
@article{Hanukoglu1977ProgesteroneMI, title={Progesterone metabolism in the pineal, brain stem, thalamus and corpus callosum of the female rat}, author={Israel Hanukoglu and H. J. Karavolas and R. Goy}, journal={Brain Research}, year={1977}, volume={125}, pages={313-324} }
Specific brain regions, namely, thalamus, tectum, tegmentum, cerebellum, medulla and pineal, from five proestrous rats were incubated for 30 min with [3H]progesterone. After reverse isotopic dilution analysis, the following metabolites were identified in all incubations by purification to constant specific activity, derivative formation and/or gas liquid chromatography trapping: [3H]5alpha-pregnane-3, 20-dione (10-20% of the starting substrate except pineal -- 0.7%), [3H]3alpha-hydroxy-5alpha… CONTINUE READING
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