Progesterone is neuroprotective after transient middle cerebral artery occlusion in male rats.

@article{Jiang1996ProgesteroneIN,
  title={Progesterone is neuroprotective after transient middle cerebral artery occlusion in male rats.},
  author={Nancy Jiang and Michael Chopp and D{\'a}niel Stein and Howard Feit},
  journal={Brain research},
  year={1996},
  volume={735 1},
  pages={101-7}
}
Progesterone (PROG) is a neurosteroid, possessing a variety of functions in the central nervous system. Exogenous PROG has been shown to reduce secondary neuronal loss in conjunction with attenuated brain edema after cerebral contusion and to reduce brain edema after focal cerebral ischemia. In the present study, we assessed the neuroprotective potential of PROG in a model of focal cerebral ischemia in the rat. Forty-eight male Wistar rats were randomly assigned to 4 groups, i.e. pretreatment… CONTINUE READING

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