Progesterone in gestational diabetes mellitus: guilty or not guilty?

  title={Progesterone in gestational diabetes mellitus: guilty or not guilty?},
  author={D. Branisteanu and C. Mathieu},
  journal={Trends in Endocrinology & Metabolism},
  • D. Branisteanu, C. Mathieu
  • Published 2003
  • Biology, Medicine
  • Trends in Endocrinology & Metabolism
  • Insulin resistance is one of the metabolic changes in pregnancy, but only a fraction of women develop overt impaired glucose tolerance or frank diabetes. Most women are able to compensate this altered metabolic state by increasing the amount of insulin produced by the pancreatic beta cells. Progesterone might well be the key to the development of gestational diabetes. Previously high progesterone levels have already been shown to be correlated with the development of glucose abnormalities in… CONTINUE READING
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