Progesterone for the prevention of preterm birth: indications, when to initiate, efficacy and safety

@article{How2009ProgesteroneFT,
  title={Progesterone for the prevention of preterm birth: indications, when to initiate, efficacy and safety},
  author={Helen Y. How and Baha M. Sibai},
  journal={Therapeutics and Clinical Risk Management},
  year={2009},
  volume={5},
  pages={55 - 64}
}
Preterm birth is the leading cause of neonatal mortality and morbidity and long-term disability of non-anomalous infants. Previous studies have identified a prior early spontaneous preterm birth as the risk factor with the highest predictive value for recurrence. Two recent double blind randomized placebo controlled trials reported lower preterm birth rate with the use of either intramuscular 17 alpha-hydroxyprogesterone caproate (IM 17OHP-C) or intravaginal micronized progesterone… CONTINUE READING
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