Progesterone fails to modulate Toxoplasma gondii replication in the RAW 264.7 murine macrophage cell line.

@article{Gayandrieu2002ProgesteroneFT,
  title={Progesterone fails to modulate Toxoplasma gondii replication in the RAW 264.7 murine macrophage cell line.},
  author={Françoise Gay-andrieu and Gr{\'e}goire Jacques No{\"e}l Cozon and Josette Ferrandiz and François Peyron},
  journal={Parasite immunology},
  year={2002},
  volume={24 4},
  pages={173-8}
}
Cell mediated immunity is very important for host defence against intracellular pathogens and many studies have shown the role of the production of nitric oxide (NO) by interferon (IFN)-gamma/lipopolysaccharide (LPS)-activated macrophages. As the progesterone level increases during pregnancy in mammals, and as previous studies have shown that progesterone inhibits inducible nitric oxide synthase (iNOS) expression and NO production, we aimed to investigate whether progesterone might modulate… CONTINUE READING