Progesterone facilitates cisplatin toxicity in epithelial ovarian cancer cells and xenografts.

Abstract

OBJECTIVES The underlying premise of these investigations was that the lipophilic hormone progesterone, which partitions into and (at relatively high concentrations) impedes the fluid mechanics of the plasmalemma, would perturb integral associations between membrane lipids and exporter pumps that otherwise confer drug resistance. That progesterone can… (More)
DOI: 10.1016/j.ygyno.2008.03.021

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Cite this paper

@article{Murdoch2008ProgesteroneFC, title={Progesterone facilitates cisplatin toxicity in epithelial ovarian cancer cells and xenografts.}, author={W. James Murdoch and Edward Alva Van Kirk and Dale D. Isaak and Youqing Shen}, journal={Gynecologic oncology}, year={2008}, volume={110 2}, pages={251-5} }