Progesterone but not estradiol 17beta potentiates local GH secretions by hormone-dependent breast cancer explants. An in vitro study.

@article{Milewicz2005ProgesteroneBN,
  title={Progesterone but not estradiol 17beta potentiates local GH secretions by hormone-dependent breast cancer explants. An in vitro study.},
  author={Tomasz Milewicz and Ewa Łucja Gregoraszczuk and Katarzyna Augustowska and Jozef Krzysiek and Krystyna Sztefko and Janusz Ryś},
  journal={Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association},
  year={2005},
  volume={113 2},
  pages={127-32}
}
The aim of this study was to evaluate the effects of treatment of breast cancer explants with tamoxifen (TMX) or RU486 on GH secretory dynamics in the presence of exogenous estrogen (E2), progesterone (P4) or both. Explants obtained during surgery were divided according to their sex steroid hormone receptor status. P4 (10(-7) M) or 17beta-estradiol (10(-5… CONTINUE READING