Progesterone and the risk of preterm birth among women with a short cervix.

  title={Progesterone and the risk of preterm birth among women with a short cervix.},
  author={Eduardo Borges da Fonseca and Ebru Çelik and Mauro Parra and Mandeep Singh and Kypros H. Nicolaides},
  journal={The New England journal of medicine},
  volume={357 5},
BACKGROUND Previous randomized trials have shown that progesterone administration in women who previously delivered prematurely reduces the risk of recurrent premature delivery. Asymptomatic women found at midgestation to have a short cervix are at greatly increased risk for spontaneous early preterm delivery, and it is unknown whether progesterone reduces this risk in such women. METHODS Cervical length was measured by transvaginal ultrasonography at a median of 22 weeks of gestation (range… 

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