Progesterone and progestins: applications in gynecology

@article{Ziegler2000ProgesteroneAP,
  title={Progesterone and progestins: applications in gynecology},
  author={D. Ziegler and R. Fanchin},
  journal={Steroids},
  year={2000},
  volume={65},
  pages={671-679}
}
Achievements obtained in infertility treatments over the past two decades have sparked interest in optimizing progesterone administration. Although progesterone is absorbed orally when ingested in micronized form, bioavailability is poor because of extensive liver metabolism. This explains why full predecidual transformation of the endometrium cannot be achieved with oral progesterone and is therefore ineffective for luteal support in in vitro fertilization (IVF). Progesterone administered non… Expand

Paper Mentions

Interventional Clinical Trial
This is a multiple dose, observer blind, randomised, parallel groups pharmacodynamic and pharmacokinetic study to assess the endometrial effects (predecidual changes) of a new… Expand
ConditionsHealthy
InterventionDrug
Progesterone use in assisted reproductive technology.
An update of luteal phase support in stimulated IVF cycles.
Metabolism of endogenous and exogenous reproductive hormones.
  • D. Grow
  • Medicine
  • Obstetrics and gynecology clinics of North America
  • 2002
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 61 REFERENCES
Uses of progesterone in clinical practice.
Vaginal progesterone in menopause: Crinone 4% in cyclical and constant combined regimens.
Oral Administration of Micronized Progesterone: A Review and More Experience
Transvaginal Administration of Progesterone
Effects of luteal estradiol on the secretory transformation of human endometrium and plasma gonadotropins.
...
1
2
3
4
5
...