44 Citations
Pharmacokinetics of the progesterone-containing vaginal tablet and its use in assisted reproduction
- Medicine, BiologySteroids
- 2000
Pharmacokinetics of Natural Progesterone Vaginal Suppository
- Biology, MedicineGynecologic and Obstetric Investigation
- 2004
It is demonstrated that vaginally administered progesterone could reach levels that are similar to those obtained in ovulatory and luteal phases, and the progestersone regimen for adequate endometrial protection and in vitro fertilization (IVF) programs still remains to be studied.
Progesterone use in assisted reproductive technology.
- Medicine, BiologyBest practice & research. Clinical obstetrics & gynaecology
- 2020
Effect of oral administration of dydrogestrone versus vaginal administration of natural micronized progesterone on the secretory transformation of endometrium and luteal endocrine profile in patients with premature ovarian failure: a proof of concept.
- Medicine, BiologyHuman reproduction
- 2007
After estrogen endometrial priming in POF patients, exogenous vaginal micronized progesterone is more effective than oral DG in creating an 'in-phase' secretory endometrium and induces significantly higher progester one and lower LH and FSH serum concentrations on day 21 of the cycle.
A Review of Luteal Support Protocols for Single Embryo Transfers: Fresh and Frozen
- Biology
- 2015
Current data suggest no difference in outcome between hormonally medicated protocols or natural cycles and that no benefit is gained by adding progesterone to the luteal phase of modified natural treatment cycles, so additional research is needed to inform the decision-making process.
Comparative study of the efficacy and tolerability of two vaginal progesterone formulations, Crinone 8% gel and Utrogestan capsules, used for luteal support.
- Medicine, BiologyFertility and sterility
- 2007
Effect of Oral versus Vaginal Administration of Estradiol and Dydrogesterone on the Proliferative and Secretory Transformation of Endometrium in Patients with Premature Ovarian Failure and Preparing for Assisted Reproductive Technology
- Medicine, BiologyDrug design, development and therapy
- 2021
Vaginal administration of E2 and DG is more effective than oral administration regarding proliferative and secretory transformation of the endometrium in POF patients and preparing for assisted reproductive technology.
Metabolism of endogenous and exogenous reproductive hormones.
- Medicine, BiologyObstetrics and gynecology clinics of North America
- 2002
Oral dydrogesterone for luteal phase support in fresh in vitro fertilization cycles: a new standard?
- Medicine, BiologyFertility and sterility
- 2018
New hormonal therapies and regimens in the postmenopause: routes of administration and timing of initiation
- MedicineClimacteric : the journal of the International Menopause Society
- 2007
The combination of non-oral administration of estradiol and local delivery of progesterone or a progestin such as levonorgestrel by means of gels, sprays, vaginal rings or intrauterine systems would represent new methods of replacement therapy for the menopausal woman, improving compliance and minimizing the risks of hormone replacement.
References
SHOWING 1-10 OF 60 REFERENCES
Effects of natural progesterone on the morphology of the endometrium in patients with primary ovarian failure.
- Medicine, BiologyHuman reproduction
- 1990
It was concluded that the vaginal route for administering micronized progesterone can be advised as the treatment of choice in patients without ovarian function.
Use of Crinone vaginal progesterone gel for luteal support in in vitro fertilization cycles.
- Medicine, BiologyFertility and sterility
- 1999
Uses of progesterone in clinical practice.
- Biology, MedicineInternational journal of fertility and women's medicine
- 1999
Studies in infertility show that vaginal progesterone in this form allows secretory transformation of the endometrium and the development of pregnancy despite providing low systemic progestersone concentrations, and fewer side effects occur when used for hormone replacement than typically encountered with progestins and oral progestone.
Vaginal progesterone in menopause: Crinone 4% in cyclical and constant combined regimens.
- Medicine, BiologyHuman reproduction
- 2000
The results indicate that both regimens using the sustained release vaginal progesterone gel controlled bleeding in HRT, combined with the lower incidence of side-effects characteristic of vaginal progestone, both vaginal progestersone regimens have the potential of improving HRT compliance.
Direct Transport of Progesterone From Vagina to Uterus
- Medicine, BiologyObstetrics and gynecology
- 2000
Luteal support after luteinizing hormone-releasing hormone agonist for in vitro fertilization: superiority of human chorionic gonadotropin over oral progesterone.
- Medicine, BiologyFertility and sterility
- 1990
Effects of luteal estradiol on the secretory transformation of human endometrium and plasma gonadotropins.
- Medicine, BiologyThe Journal of clinical endocrinology and metabolism
- 1992
In women deprived of ovarian function, administration of P only after 14 days of E2 priming prevented uterine bleeding and induced normal secretory transformations of the endometrium, but failed to suppress plasma gonadotropins.
Crinone 8% (90 mg) given once daily for progesterone replacement therapy in donor egg cycles.
- Medicine, BiologyFertility and sterility
- 1999
Pharmacokinetics and endometrial tissue levels of progesterone after administration by intramuscular and vaginal routes: a comparative study.
- Medicine, BiologyFertility and sterility
- 1994
The hormonal control of endometrial receptivity: estrogen (E2) and progesterone.
- Biology, MedicineJournal of reproductive immunology
- 1998