Progesterone and its derivatives are neuroprotective agents in experimental diabetic neuropathy: a multimodal analysis.

@article{Leonelli2007ProgesteroneAI,
  title={Progesterone and its derivatives are neuroprotective agents in experimental diabetic neuropathy: a multimodal analysis.},
  author={Emanuela Leonelli and Roberto Bianchi and Guido Cavaletti and Donatella Caruso and Donatella Crippa and Luis Miguel Garcia-Segura and Giuseppe Lauria and Valerio Magnaghi and Ilaria Roglio and Roberto Cosimo Melcangi},
  journal={Neuroscience},
  year={2007},
  volume={144 4},
  pages={1293-304}
}
One important complication of diabetes is damage to the peripheral nervous system. However, in spite of the number of studies on human and experimental diabetic neuropathy, the current therapeutic arsenal is meagre. Consequently, the search for substances to protect the nervous system from the degenerative effects of diabetes has high priority in biomedical research. Neuroactive steroids might be interesting since they have been recently identified as promising neuroprotective agents in several… CONTINUE READING
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