Progesterone Inhibits Female-Typical Receptive Behavior and Decreases Hypothalamic Estrogen and Progesterone Receptor Messenger Ribonucleic Acid Levels in Whiptail Lizards (GenusCnemidophorus)

  title={Progesterone Inhibits Female-Typical Receptive Behavior and Decreases Hypothalamic Estrogen and Progesterone Receptor Messenger Ribonucleic Acid Levels in Whiptail Lizards (GenusCnemidophorus)},
  author={John R Godwin and Vesta Hartman and Michael G. Grammer and David Crews},
  journal={Hormones and Behavior},
Female-typical sexual behavior in tetrapods is mediated primarily by estrogen and progesterone acting through intracellular receptors at specific sites in the mediobasal hypothalamus. Progesterone exerts both faciliatory and inhibitory actions on female sexual behavior and in well-studied rodent models, the inhibitory actions are exerted through downregulation of progesterone and estrogen receptors. This study examined progesterone effects on both female-typical sexual behavior and hypothalamic… 

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