Progesterone Administration Modulates Cortical TLR4/NF-κB Signaling Pathway after Subarachnoid Hemorrhage in Male Rats

@article{Wang2011ProgesteroneAM,
  title={Progesterone Administration Modulates Cortical TLR4/NF-$\kappa$B Signaling Pathway after Subarachnoid Hemorrhage in Male Rats},
  author={Z. Wang and Gang Zuo and Xiao-Yong Shi and J. Zhang and Qi Fang and G. Chen},
  journal={Mediators of Inflammation},
  year={2011},
  volume={2011}
}
Our previous study concerning brain trauma has shown that progesterone could regulate toll-like receptor 4 (TLR4) and nuclear factor-kappa B (NF-κB) signaling pathway in the brain, which also has been proved to play important roles in early brain injury (EBI) after subarachnoid hemorrhage (SAH). The aim of the current study was to investigate whether progesterone administration modulated TLR4/NF-κB pathway signaling pathway in the brain at the early stage of SAH. All SAH animals were subjected… Expand
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