Progesterone, but not β-estradiol, enhances Porphyromonas gingivalis lipopolysaccharide-induced vascular endothelial growth factor-A expression in human THP-1 monocytes

@inproceedings{Jitprasertwong2013ProgesteroneBN,
  title={Progesterone, but not β-estradiol, enhances Porphyromonas gingivalis lipopolysaccharide-induced vascular endothelial growth factor-A expression in human THP-1 monocytes},
  author={Paiboon Jitprasertwong and Niratcha Chaisomboon and Kusuma Jamdee},
  year={2013}
}
Abstract Background/purpose Progesterone and estrogen levels are elevated during pregnancy and play a role in maternal immune responses. In addition, unbalanced metabolism of growth factors has been demonstrated in pregnancy tumors. Therefore, we aimed to investigate the effect of progesterone and β-estradiol on vascular endothelial growth factor-A (VEGF-A) and basic fibroblast growth factor (bFGF) messenger RNA (mRNA) expression in THP-1 monocytes in response to Porphyromonas gingivalis… CONTINUE READING

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