Profound reduction of invariant natural killer T cells in the peripheral blood of a patient with interleukin-1 receptor-associated kinase 4 deficiency.

@article{Haraguchi2010ProfoundRO,
  title={Profound reduction of invariant natural killer T cells in the peripheral blood of a patient with interleukin-1 receptor-associated kinase 4 deficiency.},
  author={Soichi Haraguchi and Noorbibi K. Day and Nutthapong Tangsinmankong and John William Sleasman},
  journal={Immunology letters},
  year={2010},
  volume={132 1-2},
  pages={86-9}
}
We previously described a patient with a history of frequent life-threatening pneumonias, infections with bacterial pathogens, interleukin 1 receptor-associated kinase 4 deficiency, and failure to maintain antibody titers to polysaccharide antigens or to a neoantigen bacteriophage. In the present study, we show that the patient's peripheral blood… CONTINUE READING