Profound impact of gut homeostasis on chemically-induced pro-tumorigenic inflammation and hepatocarcinogenesis in rats.

@article{Zhang2012ProfoundIO,
  title={Profound impact of gut homeostasis on chemically-induced pro-tumorigenic inflammation and hepatocarcinogenesis in rats.},
  author={Hui-Lu Zhang and Le-xing Yu and Wen Yang and Liang Tang and Yan Lin and Han Wu and Bo Zhai and Ye-xiong Tan and Lei Shan and Qiong Liu and Hai-Yang Chen and Rong-yang Dai and Bi-Jun Qiu and Ya-qin He and Chao Wang and Long-Yi Zheng and Yu-qiong Li and Fu-quan Wu and Zhuyin Li and He-xin Yan and Hong-yang Wang},
  journal={Journal of hepatology},
  year={2012},
  volume={57 4},
  pages={803-12}
}
BACKGROUND & AIMS Due to its anatomic connection, the liver is constantly exposed to gut-derived bacterial products or metabolites. Disruption of gut homeostasis is associated with many human diseases. The aim of this study was to determine the role of gut homeostasis in initiation and progression of hepatocellular carcinoma (HCC). METHODS Disruption of… CONTINUE READING