Profound but transient deficits in learning and memory after global ischemia using a novel water maze test

@article{Euler2006ProfoundBT,
  title={Profound but transient deficits in learning and memory after global ischemia using a novel water maze test},
  author={Mia von Euler and Olof Bendel and Tjerk Bueters and Johan Sandin and Gabriel von Euler},
  journal={Behavioural Brain Research},
  year={2006},
  volume={166},
  pages={204-210}
}
The pyramidal CA1 neurons of the hippocampus are critically involved in spatial learning and memory. These neurons are especially vulnerable to cerebral ischemia, but in spite of this, it has been consistently difficult to show any learning and memory deficits in two-vessel occlusion models of global ischemia. Transient global ischemia was induced in adult male rats under general anaesthesia administered by artificial respiration to prevent respiratory arrest. Systemic blood pressure was… CONTINUE READING

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