Profound astrogenesis in the striatum of adult mice following nigrostriatal dopaminergic lesion by repeated MPTP administration.

Abstract

Neural progenitor cells are present in the rodent brain throughout adulthood, and can proliferate and differentiate into new neurons and/or glia to repair injury. To explore the repair processes mediated by brain progenitor cells, a selective lesion of the nigrostriatal dopaminergic pathway was induced in young adult mice by repeated administration of the… (More)

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@article{Mao2001ProfoundAI, title={Profound astrogenesis in the striatum of adult mice following nigrostriatal dopaminergic lesion by repeated MPTP administration.}, author={L Mao and Y. S. Lau and Elizabeth Petroske and J. Q. Wang}, journal={Brain research. Developmental brain research}, year={2001}, volume={131 1-2}, pages={57-65} }