Profiling the proteome of the venom from the social wasp Polybia paulista: a clue to understand the envenoming mechanism.

@article{Santos2010ProfilingTP,
  title={Profiling the proteome of the venom from the social wasp Polybia paulista: a clue to understand the envenoming mechanism.},
  author={Lucilene Delazari dos Santos and Keity Souza Santos and Jos{\'e} Roberto Aparecido Dos Santos Pinto and Nathalia Baptista Dias and Bibiana Monson de Souza and Marise Fonseca dos Santos and Jonas Perales and Gilberto B. Domont and F{\'a}bio Fernandes Morato Castro and Jorge Kalil and Mario Sergio Palma},
  journal={Journal of proteome research},
  year={2010},
  volume={9 8},
  pages={3867-77}
}
The study reported here is a classical bottom-up proteomic approach where proteins from wasp venom were extracted and separated by 2-DE; the individual protein spots were proteolytically digested and subsequently identified by using tandem mass spectrometry and database query with the protein search engine MASCOT. Eighty-four venom proteins belonging to 12 different molecular functions were identified. These proteins were classified into three groups; the first is constituted of typical venom… CONTINUE READING
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