Profiling the Anaerobic Response of C. elegans Using GC-MS

  title={Profiling the Anaerobic Response of C. elegans Using GC-MS},
  author={Jeffrey V. Butler and Robert J. Mishur and Alex F. Bokov and Kevin W. Hakala and Susan T. Weintraub and Shane L. Rea},
  booktitle={PloS one},
The nematode Caenorhabditis elegans is a model organism that has seen extensive use over the last four decades in multiple areas of investigation. In this study we explore the response of the nematode Caenorhabditis elegans to acute anoxia using gas-chromatography mass-spectrometry (GC-MS). We focus on the readily-accessible worm exometabolome to show that C. elegans are mixed acid fermenters that utilize several metabolic pathways in unconventional ways to remove reducing equivalents… CONTINUE READING