Profiling status epilepticus-induced changes in hippocampal RNA expression using high-throughput RNA sequencing

@inproceedings{Hansen2014ProfilingSE,
  title={Profiling status epilepticus-induced changes in hippocampal RNA expression using high-throughput RNA sequencing},
  author={Katelin F. Hansen and Kensuke Sakamoto and Carl R. Pelz and Soren D Impey and Karl Obrietan},
  booktitle={Scientific reports},
  year={2014}
}
Status epilepticus (SE) is a life-threatening condition that can give rise to a number of neurological disorders, including learning deficits, depression, and epilepsy. Many of the effects of SE appear to be mediated by alterations in gene expression. To gain deeper insight into how SE affects the transcriptome, we employed the pilocarpine SE model in mice and Illumina-based high-throughput sequencing to characterize alterations in gene expression from the induction of SE, to the development of… CONTINUE READING
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