Profiling retrospective thyroid function data in complete thyroidectomy patients to investigate the HPT axis set point (PREDICT-IT)

@article{Li2020ProfilingRT,
  title={Profiling retrospective thyroid function data in complete thyroidectomy patients to investigate the HPT axis set point (PREDICT-IT)},
  author={E. Li and P. Yen and Johannes W. Dietrich and M. Leow},
  journal={Journal of Endocrinological Investigation},
  year={2020},
  volume={44},
  pages={969 - 977}
}
  • E. Li, P. Yen, +1 author M. Leow
  • Published 2020
  • Medicine
  • Journal of Endocrinological Investigation
The homeostatic euthyroid set point of the hypothalamus–pituitary–thyroid axis of any given individual is unique and oscillates narrowly within substantially broader normal population ranges of circulating free thyroxine (FT4) and thyroid-stimulating hormone (TSH), otherwise termed ‘thyroid function test (TFT)’. We developed a mathematical algorithm codenamed Thyroid-SPOT that effectively reconstructs the personalized set point in open-loop situations and evaluated its performance in a… Expand

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