Profiling of the Chromatin-associated Proteome Identifies HP1BP3 as a Novel Regulator of Cell Cycle Progression.

@article{Dutta2014ProfilingOT,
  title={Profiling of the Chromatin-associated Proteome Identifies HP1BP3 as a Novel Regulator of Cell Cycle Progression.},
  author={Bamaprasad Dutta and Yan Ren and Piliang Hao and Kae Hwan Sim and Esther Sok Hwee Cheow and Sunil S Adav and James P Tam and Siu Kwan Sze},
  journal={Molecular & cellular proteomics : MCP},
  year={2014},
  volume={13 9},
  pages={
          2183-97
        }
}
The chromatin-associated proteome (chromatome) regulates cellular gene expression by restricting access of transcriptional machinery to template DNA, and dynamic re-modeling of chromatin structure is required to regulate critical cell functions including growth and replication, DNA repair and recombination, and oncogenic transformation in progression to cancer. Central to the control of these processes is efficient regulation of the host cell cycle, which is maintained by rapid changes in… CONTINUE READING
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