Profiling of molecular interactions in real time using acoustic detection.

  title={Profiling of molecular interactions in real time using acoustic detection.},
  author={Benjamin L J Godber and Mark Frogley and Marian Rehak and Alexander Sleptsov and Kevin S. J. Thompson and Yıldız Bozkurt Uludağ and Matthew A. Cooper},
  journal={Biosensors & bioelectronics},
  volume={22 9-10},
Acoustic sensors that exploit resonating quartz crystals to directly detect the binding of an analyte to a receptor are finding increasing utility in the quantification of clinically relevant analytes. We have developed a novel acoustic detection technology, which we term resonant acoustic profiling (RAP). This technology builds on the fundamental basics of the "quartz crystal microbalance" or "QCM" with several key additional features including two- or four-channel automated sample delivery… CONTINUE READING

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