Profiling of microRNAs in exosomes released from PC-3 prostate cancer cells.

@article{Hessvik2012ProfilingOM,
  title={Profiling of microRNAs in exosomes released from PC-3 prostate cancer cells.},
  author={Nina Pettersen Hessvik and Santosh Phuyal and Andreas Brech and Kirsten Sandvig and Alicia Llorente},
  journal={Biochimica et biophysica acta},
  year={2012},
  volume={1819 11-12},
  pages={1154-63}
}
Exosomes are small extracellular vesicles released to the extracellular milieu through fusion of multivesicular bodies with the plasma membrane. These vesicles contain microRNAs and might therefore be vehicles transferring genetic information between cells. The aim of this study was to investigate whether there was a sorting of microRNAs into exosomes in the prostate cancer cell line PC-3. In addition, microRNAs in PC-3 cells and in the non-cancerous prostate cell line RWPE-1 were compared… CONTINUE READING