Profiling of genes which are differentially expressed in mouse liver in response to adenoviral vectors and delivered genes

@article{Haberberger2000ProfilingOG,
  title={Profiling of genes which are differentially expressed in mouse liver in response to adenoviral vectors and delivered genes},
  author={TC Haberberger and Kenneth Kupfer and J K Murphy},
  journal={Gene Therapy},
  year={2000},
  volume={7},
  pages={903-909}
}
The effects of transgene delivery by adenoviral vectors were studied by probing a 588 gene, mouse cDNA array with mRNA derived from infected liver. The liver tissues were obtained from naive mice and mice infected with replication-deficient adenovirus, adenovirus expressing transforming growth factor β1 (TGFβ1), and adenovirus expressing connective tissue growth factor (CTGF). Expression of 98 genes was detected in the array analysis. The increased expression of the transcripts for Stat1, gamma… CONTINUE READING