Profiling of enantiopure drugs towards aryl hydrocarbon (AhR), glucocorticoid (GR) and pregnane X (PXR) receptors in human reporter cell lines.

Abstract

In the past decade, a large number of enantiopure drugs were introduced to clinical practice, since improved therapeutic effects were demonstrated for one of the enantiomers from originally racemic drug. While the therapeutic effects and safety of enantiopure drugs were tested prior to their approval, various biological enantiospecific activities of these… (More)
DOI: 10.1016/j.cbi.2013.11.018

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Cite this paper

@article{Novotn2014ProfilingOE, title={Profiling of enantiopure drugs towards aryl hydrocarbon (AhR), glucocorticoid (GR) and pregnane X (PXR) receptors in human reporter cell lines.}, author={Aneta Novotn{\'a} and Alzbeta Kamenickova and Michaela Pe{\vc}ov{\'a} and Martina Korhoňov{\'a} and Iveta Bartoňkov{\'a} and Zdenek Dvorak}, journal={Chemico-biological interactions}, year={2014}, volume={208}, pages={64-76} }