Profiling maternal plasma microRNA expression in early pregnancy to predict gestational diabetes mellitus.

@article{Zhu2015ProfilingMP,
  title={Profiling maternal plasma microRNA expression in early pregnancy to predict gestational diabetes mellitus.},
  author={Yanan Zhu and Fei Tian and Hailing Li and Youxia Zhou and Jiafeng Lu and Qinyu Ge},
  journal={International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics},
  year={2015},
  volume={130 1},
  pages={49-53}
}
OBJECTIVE To profile the differential expression of plasma miRNAs in gestational diabetes mellitus (GDM). METHODS In a pilot study conducted at a tertiary hospital in China between 2010 and 2014, peripheral blood samples were collected from women at 16-19weeks of pregnancy. Pooled samples from 10 women who were subsequently diagnosed with GDM and from 10 healthy controls were used to construct two small RNA libraries. High-throughput sequencing was performed, and differentially expressed… CONTINUE READING
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