Profiling by Image Registration Reveals Common Origin of Annelid Mushroom Bodies and Vertebrate Pallium

  title={Profiling by Image Registration Reveals Common Origin of Annelid Mushroom Bodies and Vertebrate Pallium},
  author={R. Tomer and A. Denes and K. Tessmar-Raible and D. Arendt},
  • R. Tomer, A. Denes, +1 author D. Arendt
  • Published 2010
  • Biology, Medicine
  • Cell
  • The evolution of the highest-order human brain center, the "pallium" or "cortex," remains enigmatic. To elucidate its origins, we set out to identify related brain parts in phylogenetically distant animals, to then unravel common aspects in cellular composition and molecular architecture. Here, we compare vertebrate pallium development to that of the mushroom bodies, sensory-associative brain centers, in an annelid. Using a newly developed protocol for cellular profiling by image registration… CONTINUE READING
    249 Citations
    Six3 demarcates the anterior-most developing brain region in bilaterian animals
    • 116
    Cephalopod Brains: An Overview of Current Knowledge to Facilitate Comparison With Vertebrates
    • 30
    • PDF
    Genealogical Correspondence of Mushroom Bodies across Invertebrate Phyla
    • 51
    • PDF
    Whole-organism cellular gene-expression atlas reveals conserved cell types in the ventral nerve cord of Platynereis dumerilii
    • 41
    • PDF
    Conserved patterns of axogenesis in the panarthropod brain.
    • 13
    Origin of Drosophila mushroom body neuroblasts and generation of divergent embryonic lineages
    • 60
    • Highly Influenced
    • PDF
    Brain anatomy in Diplura (Hexapoda)
    • 14


    Evolution, discovery, and interpretations of arthropod mushroom bodies.
    • 515
    • Highly Influential
    • PDF
    Evolutionary Convergence of Higher Brain Centers Spanning the Protostome-Deuterostome Boundary
    • S. Farris
    • Biology, Medicine
    • Brain, Behavior and Evolution
    • 2008
    • 44
    • PDF
    Evolution of insect mushroom bodies: old clues, new insights
    • 120
    • PDF
    Conserved Sensory-Neurosecretory Cell Types in Annelid and Fish Forebrain: Insights into Hypothalamus Evolution
    • 291
    Molecular Architecture of Annelid Nerve Cord Supports Common Origin of Nervous System Centralization in Bilateria
    • 364
    • PDF
    Early development of the Drosophila mushroom body: the roles of eyeless and dachshund.
    • 131
    • PDF
    Genes and homology in nervous system evolution: Comparing gene functions, expression patterns, and cell type molecular fingerprints
    • D. Arendt
    • Biology, Medicine
    • Theory in Biosciences
    • 2008
    • 44
    Arthropod phylogeny: onychophoran brain organization suggests an archaic relationship with a chelicerate stem lineage
    • 107
    • PDF
    Molecular markers for identified neuroblasts in the developing brain of Drosophila
    • 190
    • PDF
    Fate mapping of the mouse prosencephalic neural plate.
    • 188