Profiling and initial validation of urinary microRNAs as biomarkers in IgA nephropathy

@inproceedings{Wang2015ProfilingAI,
  title={Profiling and initial validation of urinary microRNAs as biomarkers in IgA nephropathy},
  author={Nannan Wang and Ru Bu and Zhiyu Duan and Zhang Xueguang and Pu Chen and Zuoxiang Li and Jie Wu and Guang-yan Cai and Xiangmei Chen and Santosh Patnaik},
  booktitle={PeerJ},
  year={2015}
}
Background. MicroRNAs (miRNAs) have been found in virtually all body fluids and used successfully as biomarkers for various diseases. Evidence indicates that miRNAs have important roles in IgA nephropathy (IgAN), a major cause of renal failure. In this study, we looked for differentially expressed miRNAs in IgAN and further evaluated the correlations between candidate miRNAs and the severity of IgAN. Methods. Microarray and RT-qRCR (real-time quantitative polymerase chain reaction) were… CONTINUE READING
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