Profiling and authentication of human cell lines using short tandem repeat (STR) loci: Report from the National Cell Bank of Iran.

@article{Azari2007ProfilingAA,
  title={Profiling and authentication of human cell lines using short tandem repeat (STR) loci: Report from the National Cell Bank of Iran.},
  author={Shahram Yaguti Azari and Nahid Dorostkar Ahmadi and Mahmood Jeddi Tehrani and F Askari Seyed Shokri},
  journal={Biologicals : journal of the International Association of Biological Standardization},
  year={2007},
  volume={35 3},
  pages={
          195-202
        }
}
Assurance of cell line homogeneity and capability of cell contamination detection are among the most essential steps of cell based research. Due to high discriminatory efficiency, low cost and reliability, analysis of short tandem repeats (STR) has been introduced as a method of choice for human cell line authentication. In the present study 13 Combined DNA Index System (CODIS) based STRs along with the gender determination (Amelogenin) gene were utilized to establish a reproducible approach… CONTINUE READING
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