Profiling adipocytokine secretion from creeping fat in Crohn's disease.

  title={Profiling adipocytokine secretion from creeping fat in Crohn's disease.},
  author={Gisela Paul and Andreas Schaeffler and Markus Neumeier and Alois Fuerst and Frauke Bataillle and Christa Buechler and Ulf Mueller-Ladner and Juergen Schoelmerich and Gerhard Rogler and Hans Herfarth},
  journal={Inflammatory bowel diseases},
  volume={12 6},
BACKGROUND Adipose tissue is recognized as a compartment secreting highly active molecules. Creeping fat represents a characteristic feature of Crohn's disease (CD). Proinflammatory or anti-inflammatory adipose-derived secretory products, now generally called adipocytokines, may play a role in the pathogenesis of CD. MATERIALS AND METHODS Adipose tissue specimens were obtained from creeping fat contiguous to the involved intestine of 10 patients with CD. Mesenteric adipose tissue specimens… CONTINUE READING


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