Profilin regulates F-actin network homeostasis by favoring formin over Arp2/3 complex.

Abstract

Fission yeast cells use Arp2/3 complex and formin to assemble diverse filamentous actin (F-actin) networks within a common cytoplasm for endocytosis, division, and polarization. Although these homeostatic F-actin networks are usually investigated separately, competition for a limited pool of actin monomers (G-actin) helps to regulate their size and density… (More)
DOI: 10.1016/j.devcel.2014.10.027

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Cite this paper

@article{Surez2015ProfilinRF, title={Profilin regulates F-actin network homeostasis by favoring formin over Arp2/3 complex.}, author={Cristian Su{\'a}rez and Robert T. Carroll and Thomas A. Burke and Jenna R Christensen and Andrew J Bestul and Jennifer A. Sees and Michael L Luke James and Vladimir Sirotkin and David R Kovar}, journal={Developmental cell}, year={2015}, volume={32 1}, pages={43-53} }