Profiles of neuromuscular diseases. Spinal muscular atrophy.

  title={Profiles of neuromuscular diseases. Spinal muscular atrophy.},
  author={Gregory T Carter and Richard Ted Abresch and William M Fowler and Edward R. Johnson and David D Kilmer and Craig M. McDonald},
  journal={American journal of physical medicine & rehabilitation},
  volume={74 5 Suppl},
Forty-five individuals with spinal muscular atrophy (SMA) types II and III were evaluated prospectively over a 10-yr period to develop an impairment and disability profile. SMA II subjects showed marked weakness and progressive decline of strength. Mean manual muscle test (MMT) score for all muscles combined was 2.3 +/- 0.6, with a decline in strength of -0.24 MMT units per decade. SMA III individuals had a relatively static or very slowly progressive course and were far stronger. Mean MMT… CONTINUE READING
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