Profiles of neuromuscular diseases. Myotonic dystrophy.

  title={Profiles of neuromuscular diseases. Myotonic dystrophy.},
  author={Edward R. Johnson and Richard Ted Abresch and Gregory T Carter and David D Kilmer and William M Fowler and B J Sigford and Richard L Wanlass},
  journal={American journal of physical medicine & rehabilitation},
  volume={74 5 Suppl},
Ninety-two individuals with myotonic dystrophy (MD) were evaluated prospectively over a 10-yr period and separated into two types, 75 noncongenital (NC-MD) and 17 congenital (C-MD) MD. Muscle weakness was relatively mild and similar in both types, 4.0 +/- 0.7 manual muscle test (MMT) scores for NC-MD and 3.8 +/- 0.7 in C-MD. However, weakness was progressive in the former, -0.36 MMT units per decade, and nonprogressive in C-MD. Weakness was usually generalized in both types, with no significant… CONTINUE READING