Profiles of cytokine expression in radicular cyst-lining epithelium examined by RT-PCR.

  title={Profiles of cytokine expression in radicular cyst-lining epithelium examined by RT-PCR.},
  author={Mitsuhiro Ohshima and Tsutomu Nishiyama and Katsushi Tokunaga and Shuichi Sato and Masao Maeno and Kichibee Otsuka},
  journal={Journal of oral science},
  volume={42 4},
Levels of messenger RNA (mRNA) extracted from five samples of radicular cyst-lining epithelium were analyzed for cytokines, growth factors and epithelial cell growth-related receptors by RT-PCR. All five samples expressed IL-1alpha, -1beta, IL-6, IL-8, IL-11, TGF-beta1, PDGF-A and aFGF, and receptors for EGF (c-erbB), KGF, HGF (c-met) and IL-6. Some of the specimens expressed MIP-1alpha, RANTES, GM-CSF, M-CSF, TNF-alpha, PDGF-B and bFGF, but no expression of IL-2, IL-4, IFN-gamma, IGF-I, EGF… CONTINUE READING

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