Profibrinolytic, antithrombotic, and antiinflammatory effects of an insulin-sensitizing strategy in patients in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial.

@article{Sobel2011ProfibrinolyticAA,
  title={Profibrinolytic, antithrombotic, and antiinflammatory effects of an insulin-sensitizing strategy in patients in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial.},
  author={B. E. Sobel and Regina M. Hardison and Saul M. Genuth and Maria M Brooks and Robert McBane and David J. Schneider and Richard E. Pratley and Kurt Huber and Robert A Wolk and Ashok Krishnaswami and Robert L. Frye},
  journal={Circulation},
  year={2011},
  volume={124 6},
  pages={695-703}
}
BACKGROUND Effects were compared in patients in the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial of 2 mechanistically different strategies for treatment of hyperglycemia, insulin-sensitizing and insulin-providing strategies, on biomarker profiles reflecting the balance between fibrinolysis and thrombosis and the intensity of inflammation implicated in diabetic vasculopathy. METHODS AND RESULTS A total of 2368 patients with type 2 diabetes mellitus and… CONTINUE READING
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