Proenkephalin peptide F immunoreactivity in different circulatory biocompartments after exercise

  title={Proenkephalin peptide F immunoreactivity in different circulatory biocompartments after exercise},
  author={Jill A Bush and Andrea M. Mastro and William J. Kraemer},
Responses of proenkephalin Peptide F to aerobic exercise stress in the plasma and white blood cell biocompartments
Exercise and Endogenous Opiates
The elevation in βE appears to help modify the immune response, alter blood pressure, pain, and assists with blood glucose regulation during exercise, with both genders being comparable after aerobic training.
Endogenous Opiates and Exercise-Related Hypoalgesia
More research is needed dealing with endogenous opioids and exercise, especially in the CNS compartment, to help elucidate how exercise influences hypoalgesia and immune function.
Endogenous opiates and behavior: 2006
The Stress Response to an Acute Heavy Resistance Exercise Protocol


Changes in plasma proenkephalin peptide F and catecholamine levels during graded exercise in men.
The maximum epinephrine and norepinephrine levels were found at 100% exercise intensity, with a precipitous drop in the levels at 5 min of recovery, whereas at rest the trained group had peptide F levels almost twice the level of the untrained group, whereas all other variables measured were the same.
The effects of graded exercise on plasma proenkephalin peptide F and catecholamine responses at sea level
The data demonstrate that exercise stress increases plasma peptide F immunoreactivity levels at sea level and show that sea-level response patterns to graded exercise are similar to those previously observed at moderate altitude.
Enkephalin-containing peptides processed from proenkephalin significantly enhance the antibody-forming cell responses to antigens.
Test results suggest that the proenkephalin-derived ECPs are physiologically important modifiers of the humoral immune response and provide evidence that the effects are mediated through T cells rather than B cells.
Effects of high-intensity cycle exercise on sympathoadrenal-medullary response patterns.
The data show that brief high-intensity exercise results in differential response patterns of catecholamines and proenkephalin peptide F immunoreactivity.
Nonopiate active proenkephalin‐derived peptides are secreted by T helper cells
Recent investigations have shown that the neuroendocrine and immune systems profoundly affect each other. In part, these interactions occur via common chemical messengers and receptors. One possible
Processing of Proenkephalin in Adrenal Chromaffin Cells
  • S. Wilson
  • Biology, Chemistry
    Journal of neurochemistry
  • 1991
The results suggest that the full range of proenkephalin fragments normally found in the adrenal medulla (up to 23.3 kDa) represents final processing products of the tissue and that termination of processing may depend on the co‐storage of catecholamines.
Exercise and recovery responses of adrenal medullary neurohormones to heavy resistance exercise.
The results indicate that the adrenal medulla was activated in response to the acute stress of both types of heavy resistance exercise, and during longer recovery periods, the Adrenal medullary neurohormones was also active above baseline conditions as increased concentrations of proenkephalin fragments were detected in the circulation.