Products of the iterative polyketide synthases in 9- and 10-membered enediyne biosynthesis.

Abstract

The iterative polyketide synthases from the biosynthetic pathways of three enediyne natural products were examined. The results established the all-trans conjugated pentadecaheptanene as the only major product shared by the PKSs. The experiments further revealed some intrinsic differences among the PKSs by demonstrating the formation of different by-products.

DOI: 10.1039/b916751j

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Cite this paper

@article{Sun2009ProductsOT, title={Products of the iterative polyketide synthases in 9- and 10-membered enediyne biosynthesis.}, author={Huihua Sun and Rong Kong and Di Zhu and Min Lu and Qiang Ji and C. W. Liew and Julien Lescar and Guofu Zhong and Zhao-Xun Liang}, journal={Chemical communications}, year={2009}, volume={47}, pages={7399-401} }