Productive infection maintains a dynamic steady state of residual viremia in human immunodeficiency virus type 1-infected persons treated with suppressive antiretroviral therapy for five years.

@article{Havlir2003ProductiveIM,
  title={Productive infection maintains a dynamic steady state of residual viremia in human immunodeficiency virus type 1-infected persons treated with suppressive antiretroviral therapy for five years.},
  author={Diane V. Havlir and Matthew C. Strain and Mario Clerici and Caroline Ignacio and Daria Lucia Trabattoni and Pasquale Ferrante and Joseph K Wong},
  journal={Journal of virology},
  year={2003},
  volume={77 20},
  pages={
          11212-9
        }
}
To provide insight into the dynamics and source of residual viremia in human immunodeficiency virus (HIV) patients successfully treated with antiretroviral therapy, 14 intensely monitored patients treated with indinavir and efavirenz sustaining HIV RNA at <50 copies/ml for >5 years were studied. Abacavir was added to the regimen of eight patients at year 5. After the first 9 months of therapy, HIV RNA levels had reached a plateau ("residual viremia") that persisted for over 5 years. Levels of… CONTINUE READING
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