Production of the secondary metabolites γ-aminobutyric acid and monacolin K by Monascus

  title={Production of the secondary metabolites γ-aminobutyric acid and monacolin K by Monascus},
  author={Y C Su and Jyh-Jye Wang and Tzu-Tsen Lin and Tzu-Ming Pan},
  journal={Journal of Industrial Microbiology and Biotechnology},
γ-Aminobutyric acid (GABA), a hypotensive agent, and monacolin K, a cholesterol-lowering drug, can be produced by Monascus spp. Under optimal culture conditions, the products of fermentation using Monascus spp. may serve as a multi-functional dietary supplement and can prevent heart disease. In this study, Monascus purpureus CCRC 31615, the strain with the highest amount of monacolin K, was identified from 16 strains using solid fermentation. Its GABA productivity was particularly high… CONTINUE READING
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