Production of slow responses in canine cardiac Purkinje fibers exposed to reduced pH.

@article{Davis1976ProductionOS,
  title={Production of slow responses in canine cardiac Purkinje fibers exposed to reduced pH.},
  author={L. Douglas Davis and Patrick Helmer and Fiona C. Ballantyne},
  journal={Journal of molecular and cellular cardiology},
  year={1976},
  volume={8 1},
  pages={
          61-76
        }
}
Abstract Isolated canine papillary muscle-false tendon tissue preparations were exposed to reduced pH at a level of 6.0 or 5.2. Effects on the transmembrane potential of Purkinje fibers and ventricular muscle fibers were recorded. Ventricular fibers were not significantly altered by these levels of pH relative to the changes observed in Purkinje fibers. In Purkinje fibers acid perfusion initially caused decreases in maximum diastolic potential, rising velocity and overshoot and an increase in… CONTINUE READING
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